The Epidemiology of Post-Traumatic Stress Disorder and Alcohol Use Disorder Alcohol Research: Current Reviews
These recollections might occur through intrusive memories, nightmares, or, in severe cases, flashbacks. During flashbacks, the person might momentarily believe and act as if they were back at the time of the event, experiencing it again. Smith and Cottler, in The Epidemiology of Post-Traumatic Stress Disorder and Alcohol Use Disorder, describe the changes in the Diagnostic and Statistical Manual of Mental Disorders (DSM) definitions of AUD and PTSD. They review key surveys that have measured these disorders, the possible relationships between the two disorders, the risk factors, and which populations are at risk.
Concurrent treatment of PTSD and substance use disorders using prolonged exposure (COPE)
Antidepressants, such as selective serotonin reuptake inhibitors (SSRIs), can help alleviate symptoms of depression and anxiety. Medications that reduce alcohol cravings or deter alcohol consumption, such as naltrexone, may also be considered as part of the treatment plan. When treating co-occurring PTSD and alcohol use disorder, it is essential to address both conditions simultaneously.
Race and Ethnicity Considerations Related to AUD and PTSD
- There has been a recent increase in studies examining the efficacy of integrated treatments that combine PE with cognitive-behavioral SUD approaches.
- Many people feel extreme fear during or after witnessing or experiencing potentially traumatic events, such as war, accidents, natural disasters or sexual violence.
- Alcohol use also causes its own problem, related to both mental and physical health.
- When combined with substance abuse, these symptoms can worsen, making it difficult for individuals to manage their lives.
- Research was conducted with female participants only, a group that is at greater risk for PTSD but at reduced risk for alcohol problems (Breslau 2002; Kessler et al. 1997).
The presence of two to three symptoms indicates mild AUD, four to five symptoms indicate moderate AUD, and six or more symptoms indicate severe AUD. PTSD, or Post-Traumatic Stress Disorder, is a mental health condition that can develop after experiencing or witnessing a traumatic event. It is characterized by symptoms such as intrusive thoughts or memories, hyperarousal, and avoidance of triggers. These symptoms can persist for months or even years after the traumatic event, significantly impacting a person’s daily life. It occurs when the brain’s normal response to stress becomes impaired after a traumatic event.
- With regard to behavioral treatments, exposure-based interventions are recommended given the greater improvement in PTSD symptoms observed, coupled with significant reductions in SUD severity experienced.
- Additional interventions that integrate cognitive behavioral and other therapeutic approaches include emotion-focused therapy79 and brief eclectic psychotherapy.80 The empirical literature on these approaches is limited, but the research demonstrates promising findings.
- The studies that examined medications targeting PTSD all tested selective serotonin reuptake inhibitors (SSRIs) and none observed a between-group difference in AUD or PTSD outcomes, although trends in PTSD improvement were observed in participants treated with sertraline.
- It is currently being explored among individuals with co-occurring alcohol use disorder and PTSD.
Treatments for AUD
In other words, you may begin using alcohol as a way to cope with PTSD symptoms, but it becomes a dangerous learned behavior. Recent evidence has also suggested a role in the underlying neurobiology of both PTSD and =https://ecosoberhouse.com/ AUD for glutamate and GABA, which are the most prevalent neurotransmitters in the brain. Glutamate is the most abundant excitatory neurotransmitter while GABA is the main inhibitory neurotransmitter.
Substance Use Disorders in Patients With Posttraumatic Stress Disorder: A Review of the Literature
- Over time, the body and mind can become dependent on alcohol, requiring larger quantities to feel the same relief.
- Medication is available to assist with PTSD symptoms that can cause setbacks like intrusive nightmares.
- U.S. surveys, such as the St. Louis sample of the ECA,8 the NCS,16 and the NESARC,23 have consistently found relationships between alcohol problems and PTSD.
- An estimated 3.9% of the world population has experienced PTSD at some point in their lives (2).
N-acetylcysteine (NAC) is an amino acid derivative supplement used for acetaminophen toxicity and Substance abuse as a mucolytic for chronic pulmonary conditions. NAC restores substance-induced glutamatergic dysregulation and has shown some modest efficacy in reducing cocaine use and craving 83. In one recent clinical trial, adolescents receiving 1200 mg NAC twice daily were twice as likely to have cannabinoid-free urine drug screens compared to those randomized to receive placebo 84.
What are the symptoms of PTSD?
One study (Petrakis et al. 2012) found that the active control, desipramine, was more effective than the serotonergic medication in terms of alcohol use outcomes. Desipramine (and the other tricylic antidepressants) are considered second line medications by the VA/DoD Clinical Practice Guidelines (The Management of Substance Abuse Use Disorders Working Group 2009). Despite the contradictory results, this review suggests that individuals with AUD and comorbid PTSD can safely be prescribed medications used in non-comorbid populations and patients improve with treatment. Given the high rates of dropout reported across studies and treatment types, research is needed to enhance retention among individuals with AUD/PTSD. Relatedly, the definition of a treatment “completer” needs to be better standardized, as it is difficult to interpret and compare treatment outcomes across studies when the results are based on patients who received widely different amounts of the prescribed treatment.
Psychological interventions for PTSD may also include real or imagined exposure to triggers that may evoke traumatic memories. Activated innate immune response is also noted in other psychiatric disorders, such as major depression (MD) and bipolar affective disorder, which are often comorbid with PTSD 31. Therefore, the interaction of co-occurring disorders is important to consider in otherwise heterogeneous psychiatric patient populations. Recently, Lindqvist et al. 32 reported that the inflammatory rise in PTSD among war veterans could not be explained by early life stress or depressive symptomatology, suggesting independent associations between immune activation and PTSD pathophysiology.
Treatment Options for Co-Occurring PTSD and Alcohol Use Disorder
Prazosin has been explored in the treatment of SUD and PTSD separately, but only recently in the treatment of co-occurring SUD and PTSD. Prazosin has demonstrated efficacy to reduce PTSD-related nightmares and daytime hyperarousal symptoms, and to improve sleep among individuals with PTSD 27, 78. Among individuals with single alcohol use disorder diagnosis, prazosin has been shown to reduce alcohol consumption and reduce craving to alcohol cues 79, 80. In a small randomized controlled trial comparing prazosin to placebo in individuals with co-occurring alcohol use disorder and PTSD, improvements in drinking outcomes favoring prazosin emerged, but no significant between-groups differences were found with regard to PTSD symptoms 81. However, another recent clinical trial found no advantage of prazosin (16 mg daily) over placebo in reducing PTSD symptoms, sleep disturbances, or drinking outcomes over 12 weeks. These null findings suggest that alcohol consumption may interfere with prazosin’s efficacy in improving PTSD symptoms 82•.
Prevalence Surveys Outside the United States
Complex trauma ptsd and alcohol abuse and AUD are often intertwined, as childhood trauma increases the risk of developing AUD. According to a 2023 study involving female participants, dissociation increases suicidal behavior and is a mediator between childhood sexual abuse and suicidal behavior. Our state-specific resource guides offer a comprehensive overview of drug and alcohol addiction treatment options available in your area. Working with your doctor on the best way to reduce or stop your drinking makes cutting back on alcohol easier. You may drink because you think using alcohol will help you avoid bad dreams or how scary they are.